NITROUS OXIDE - AN OVERVIEW

The final proposed mechanism of RBC vasodilation during the existence of nitrite would be the reduction of nitrite to NO by Hb. Brooks first studied the nitrite Hb interaction in 1937 which do the job was later on prolonged by Doyle in 1981 (Brooks, 1937; Doyle et al., 1981). Nitrite reacts with deoxygenated Hb to form metHb and NO (Brooks, 1937; D